Phenome Health — The Human Phenome Initiative

our work

Building the scientific infrastructure and partner ecosystem required to understand, predict and improve human health.

The Human Phenome initiative is built on three foundations

Knowledge

Technologies to interrogate and interpret biological complexity

Actionability

Partner organizations capable of recruiting participants and translating insights into impact

Information

Longitudinal human health datasets

Foundation 01

Building unique human data assets

Arivale Data Asset

Arivale proved that integrating multimodal data to guide behavioral interventions improved the health of participants–laying the groundwork for the design of future HPI cohorts.

Arivale Data Asset

Arivale proved that integrating multimodal data to guide behavioral interventions improved the health of participants–laying the groundwork for the design of future HPI cohorts.

a thermometer, pills, and a bottle on a table

BRISK (Biomedical Research Institute for Scientific Knowledge) - T2D

Mapping molecular subtypes of type 2 diabetes to personalize strategies that minimize complications and disease burden–furthering the data-driven health approach of the HPI.

BRISK (Biomedical Research Institute for Scientific Knowledge) - T2D

Mapping molecular subtypes of type 2 diabetes to personalize strategies that minimize complications and disease burden–furthering the data-driven health approach of the HPI.

Curved vibrant gradient with ribbed texture

TIME (Temporal Investigation of Multimodal Elements)

Mapping system dynamics of omics signatures to contextualize current data snapshots into moving scenes–creating a foundational interpretation layer for the HPI.

TIME (Temporal Investigation of Multimodal Elements)

Mapping system dynamics of omics signatures to contextualize current data snapshots into moving scenes–creating a foundational interpretation layer for the HPI.

Deep Phenotyping of Pregnancy (DP3)

Multiomics analysis of pregnancy identifies early markers for risks of complications and informs new risk mitigation strategies–extending the HPI's data-driven approach into the earliest stage of life.

Deep Phenotyping of Pregnancy (DP3)

Foundation 02

Building the technology infrastructure

Phenome Health's Technology Infrastructure

Harmonizing siloed multiomics from existing and emerging data to create interoperability–feeding the HPI with tools required to leverage data from around the globe.

Phenome Health's Technology Infrastructure

Harmonizing siloed multiomics from existing and emerging data to create interoperability–feeding the HPI with tools required to leverage data from around the globe.

Foundation 03

Building real-world deployment capabilities

a sculpture of a man's head made of colored wires

HOPE (Health Optimization through Phenomic Exploration)-AD.

Evidence-based lifestyle approaches work to prevent Alzheimer's disease in at-risk individuals–building strategies into the HPI to intervene before disease initiates.

HOPE (Health Optimization through Phenomic Exploration)-AD.

Evidence-based lifestyle approaches work to prevent Alzheimer's disease in at-risk individuals–building strategies into the HPI to intervene before disease initiates.

DRIVE (Data Driven Rural Interventions for Vitality & Endurance)

Deploying Phenome Health's technology to improve health in rural populations–amplifying the HPI with sustainable engagement strategies.

DRIVE (Data Driven Rural Interventions for Vitality & Endurance)

Deploying Phenome Health's technology to improve health in rural populations–amplifying the HPI with sustainable engagement strategies.

BETA (Beta cell Evaluation Through data driven Assessments)

Developing scalable, cost-effective, digital health tools to monitor diabetes progression–producing accessible technologies to build out the HPI.

BETA (Beta cell Evaluation Through data driven Assessments)

Developing scalable, cost-effective, digital health tools to monitor diabetes progression–producing accessible technologies to build out the HPI.

VOICE (Vocal Optimization Informing Cardiac Event prevention)

Identifying vocal signatures that predict cardiac events to stop them before they happen–embedding advanced scalable monitoring technology into the HPI.

VOICE (Vocal Optimization Informing Cardiac Event prevention)

Identifying vocal signatures that predict cardiac events to stop them before they happen–embedding advanced scalable monitoring technology into the HPI.